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(Solved): The four DNA molecules here are the same except for a single base pair mutation boxed in each seque ...




The four DNA molecules here are the same except for a single base pair mutation boxed in each sequence. These molecules repre
first position (5 end)
U
U
UUU
UCU
UUC
UCC
UUA
UCA
UUG
UCG
CUU
CCU
CUC
CCC
CUA
CCA
CUG
CCG
AUU
ACU
AUC lle
ACC
AUA
ACA
AUGT
T/F: The template strand for this gene is the top strand as shown in the image.
Select one:
True
O False
Which of these mutat
Which of these mutations would lead to a single amino acid change in the protein produced from this gene (a missense mutation
The four DNA molecules here are the same except for a single base pair mutation boxed in each sequence. These molecules represent a small portion of a larger eukaryotic gene. For each sequence, the bolded, underlined base pair is the starting point of transcription. The promoter for this gene is not shown, but would be somewhere to the right of your computer screen. Transcribe and translate each of the sequences using the given codon chart then respond to the questions below. Wild Type 5' ATTATGGCTCATGA 3' 3' TAATACCGAGTACI 5' Mutation 1 5' ATTATGGCTCATAA 3¹ 3' TAATACCGAGTATI 5' Mutation 2 5' ATTATGGCTCACGA 3' 3' TAATACCGAGTGCI 5' Mutation 3 5' ATTATAGCTCATGA 3' 3' TAATATCGAGTACI 5' first position (5' end) U U UUU UCU UUC UCC UUA UCA UUG UCG CUU CCU CUC CCC CUA CCA CUG CCG AUU ACU AUC lle ACC AUA ACA AUGT Met ACG GUU GCU GUC GCC G Val Ala GUA GCA GUG GCG Chain-terminating or "nonsense" codons. Phe Leu second position C A UAU Tyr UAC UAA stop UAG stop CAU His CAC CAA Gin CAG AAU Asn AAC AAA Lys AAG GAU Asp GAC GAA Glu GAG Leu Ser Pro Thr G UGU Cys UGC UGA stop UGG Trp CGU CGC CGA CGG AGU AGC AGA AGG GGU GGC GGA GGG Arg Ser Arg Gly C A G U C G ???? UCAG ? third position (3' end) T/F: The template strand for this gene is the top strand as shown in the image. Select one: True O False Which of these mutations would not change the sequence of the protein produced by this gene? O a. Mutation 1 O b. Mutation 2 O c. Mutation 3 O d. More than one of these Oe. None of these Which of these mutations could lead to a change in the reading frame used by the ribosome when translating the RNA produced from this gene? a. Mutation 1. b. Mutation 2 O c. Mutation 3 Od. More than one of these O e. None of these Which of these mutations would lead to a single amino acid change in the protein produced from this gene (a missense mutation)? Oa. Mutation 1 O b. Mutation 2. c. Mutation 3. O d. More than one of these Oe. None of these Refer to the wild type sequence above. Which of the following amino acids would be incorporated into the polypeptide synthesized from the normal DNA sequence? O a. Ala O b. lle O c. Leu Od. His Oe. More than one of these f. None of these


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