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(Solved): Sif and her husband Anton fear their unborn child will have Cystic Fibrosis, a monogenic disorder w ...
Sif and her husband Anton fear their unborn child will have Cystic Fibrosis, a monogenic disorder with an autosomal recessive mode of inheritance commonly caused by mutations in the CFTR gene. Their fetus is screened for the F508del mutation using PCR. The PCR product from the normal allele is 84 base pairs. Look at the PCR analysis result below. a) What is the genotype of the fetus and explain how you determined this using the PCR result below. b) What is the phenotype of the fetus? c) Will the fetus have cystic fibrosis? Explain why/why not.