(Solved): Q5. (7 marks) The reaction between nicotineamide mononucleotide and ATP to form nicotineamide-aden ...

Q5. (7 marks) The reaction between nicotineamide mononucleotide and ATP to form nicotineamide-adenine dinucleotide and pyrophosphate is catalyzed by the enzyme nicotinamide mononucleotide adenylyltransferase. The following table provides typical data obtained at a pH of 5 and 7.5. The substrate, S, is nicotinamide mononucleotide and the initial rate, $$\mathrm{v}$$, is the $$?\mathrm{mol}$$ of nicotinamide-adenine dinucleotide formed per minute. a. What is the $${\mathrm{V}}_{\mathrm{m}}\&{\mathrm{K}}_{\mathrm{m}}$$ for each of these $$\mathrm{pH}$$ ? b. Did these values change with pH? If so, then why?