(Solved): Put the events occurring at the neuromuscular junction into the right order. Acetylcholine is relea ...
Put the events occurring at the neuromuscular junction into the right order. Acetylcholine is released from the axon terminal and diffuses across the synaptic cleft towards the motor plate of a muscle cell. Voltage-gated calcium channels open in the plasma membrane of motor neuron. Sodium ions enter the muscle cell via ion channels open within chemically-activated ACh receptors (ligand activation) Depolarization of the sarcolemma of the the motor end plate: because of sodium ion influx, the cytosol right underneath the end plate membrane becomes more positive than above in the synaptic cleft. From the interstitial fluid, calcium ions enter the axon terminal of a motor neuron. A muscle action potential is generated in the region of the motor end plate. A muscle action potential runs along the entire sarcolemma including the T-tubules. A nerve action potential reaches the axon terminal of the motor neuron. Calcium ions induce fusion of synaptic vesicles containing acetylcholine with the plasma membrane of the axon terminal. Acetylcholine binds to acetylcholine receptors located on the motor end plate of the muscle cell.
Here is the correct order:Here is the correct order of events occurring at the neuromuscular junction:A nerve action potential reaches the axon terminal of the motor neuron.Voltage-gated calcium channels open in the plasma membrane of the motor neuron.