(Solved):   please help on all of these, thanks. The pedigree shown here is for a family affected by th ...

 

please help on all of these, thanks.

The pedigree shown here is for a family affected by the nail-patella syndrome (NPS), an autosomal dominant disorder that is genetically linked with the ABO blood type locus. What is the phased genotype of the mother (I-2)? ( \( N \) : NPS disease allele, and \( \boldsymbol{n} \) : wild-type allele) Generation I Generation II \[ \begin{array}{l} I^{\mathrm{A}} n / i n \\ I^{\mathrm{B}} N / i n \\ I^{\mathrm{B}} N / I^{\mathrm{B}} n \\ I^{\mathrm{B}} n / i N \\ I^{\mathrm{B}} n / I^{\mathrm{A}} N \end{array} \] The pedigree shown here is for a family affected by the nail-patella syndrome (NPS), an autosomal dominant disorder that is genetically linked with the ABO blood type locus. What is the phased genotype of the father (I-1)? ( \( N \) : NPS disease allele, and \( n \) : wild-type allele) Generation I Generation II \( I^{A} n / I^{A} n \) \( I^{\mathrm{A}} N / i N \) \( I^{A} n / i n \) \( I^{\mathbf{A}} \boldsymbol{N} / \boldsymbol{I}^{\mathbf{A}} \boldsymbol{N} \) \( I^{\mathrm{A}} N / i n \) The pedigree shown here is for a family affected by the nail-patella syndrome (NPS), an autosomal dominant disorder that is genetically linked with the ABO blood type locus. What is the phased genotype of the first child (II-1)? Is he a recombinant or a non-recombinant? ( \( N \) : NPS disease allele, and \( \boldsymbol{n} \) : wild-type allele) Generation I Generation II It cannot be determined. Not enough information. His phased genotype is \( \boldsymbol{I}^{\mathbf{A}} \boldsymbol{N} / \boldsymbol{i} \boldsymbol{n} \) and he is a non-recombinant. His phased genotype is \( \boldsymbol{I}^{\mathbf{A}} \boldsymbol{N} / \boldsymbol{i} \boldsymbol{n} \) and he is a recombinant. His phased genotype is \( \boldsymbol{I}^{\mathbf{A}} \boldsymbol{n} / \boldsymbol{i} \boldsymbol{N} \) and he is a recombinant. His phased genotype is \( \boldsymbol{I}^{\mathbf{A}} \boldsymbol{n} / \boldsymbol{i} \boldsymbol{N} \) and he is a non-recombinant. The pedigree shown here is for a family affected by the nail-patella syndrome (NPS), an autosomal dominant disorder that is genetically linked with the \( \mathrm{ABO} \) blood type locus. What is the phased genotype of the last child (II-6)? Is she a recombinant or a non-recombinant? ( \( \boldsymbol{N} \) : NPS disease allele, and \( \boldsymbol{n} \) : wild-type allele) Her phased genotype is \( \boldsymbol{I}^{\mathbf{A}} \boldsymbol{n} / \boldsymbol{i} \boldsymbol{n} \), and she is a recombinant. Her phased genotype is \( \boldsymbol{I}^{\mathbf{A}} \boldsymbol{n} / \boldsymbol{I}^{\mathbf{A}} \boldsymbol{n} \), and she is a non-recombinant. It cannot be determined. Not enough information. Her phased genotype is \( \boldsymbol{I}^{\mathbf{A}} \boldsymbol{n} / \boldsymbol{i} \boldsymbol{n} \), and she is a non-recombinant. Her phased genotype is \( \boldsymbol{I}^{\mathbf{A}} \boldsymbol{n} / \boldsymbol{I}^{\mathbf{A}} \boldsymbol{n} \), and she is a recombinant.