Home /
Expert Answers /
Chemistry /
nbsp-nbsp-consider-the-reaction-of-3-cyclopenten-1-one-with-neutral-propan-2-amine-also-pa408
(Solved):
Consider the reaction of 3-cyclopenten-1-one with neutral propan-2-amine (also ...
Consider the reaction of 3-cyclopenten-1-one with neutral propan-2-amine (also called isopropylamine). 1st attempt Part 1 (1 point) Draw the expected major product of this reaction. Include all lone pairs and \( \mathrm{H} \) atoms connected to heteroatoms.
Draw the first step and resulting intermediate that lead to the major product. Include all lone pairs and \( \mathrm{H} \) atoms connected to heteroatoms.
Which factors contribute to the formation of the major product over the minor product? Choose one or more: A. A localized negative charge on \( \mathrm{O} \), which is more electronegative than \( \mathrm{C} \), is lower energy than a negative charge delocalized over \( \mathrm{O} \) and \( \mathrm{C} \) atoms. B. The amine adds reversibly to the unsaturated ketone. C. An unstable carbanion forms from conjugate addition. D. The amine nucleophile is uncharged. E. 1,2-addition gives an intermediate with a single negative charge, while 1,4-addition gives a zwitterion.