(Solved): Fluorescence recovery after photobleaching (FRAP) is a method that allows super-resolution imaging ...

Fluorescence recovery after photobleaching (FRAP) is a method that allows super-resolution imaging of fluorescently-labelled samples. involves photobleaching of all the fluorophores in a sample and then observing the recovery of fluorescence in the entire sample. involves photobleaching of a portion of the fluorophores in a sample and then observing the recovery of fluorescence in the bleached area. is most effective when used in samples that are fixed (dead) and subjected to thin sectioning.