(Solved): Fetal hemoglobin consists of 2 alpha chains and 2 gamma chains. Residue 143 in the beta chain of m ...

Fetal hemoglobin consists of 2 alpha chains and 2 gamma chains. Residue 143 in the beta chain of maternal hemoglobin (see below) is a histidine and in the gamma chain it is a serine. Which one of the following statements is TRUE? B? 3 Nx BPG e Wal C Binding of BPG to deoxyHb. OA) The mutation of His to Ser increases the binding of BPG and so decreases the affinity of fetal hemoglobin for oxygen relative to maternal hemoglobin. O B) The mutation of His to Ser decreases the binding of BPG and so decreases the affinity of fetal hemoglobin for oxygen relative to maternal hemoglobin. OC) The mutation of His to Ser increases the binding of BPG and so increases the affinity of fetal hemoglobin for oxygen relative to maternal hemoglobin. OD) The mutation of His to Ser decreases the binding of BPG and so increases the affinity of fetal hemoglobin for oxygen relative to maternal hemoglobin.