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(Solved): Cerebellar abiotrophy (CA) is a recessive, genetic neurological disease found in the Arabian horse ...
Cerebellar abiotrophy (CA) is a recessive, genetic neurological disease found in the Arabian horse breed. If the incidence of this disease is about 1 in 400 Arabian horses, estimate the frequency of carriers in a population in Hardy-Weinberg equilibrium. The recessive allele is represented by c and the normal, wildtype allele is represented by C. The frequency of genotype CC (homozygous normal) is represented by $p?2$. The frequency of genotype cc (homozygous CA) is represented by $q?2$. The allelic frequency of C is represented by $p$. The allelic frequency of c is represented by $q$. To find the frequency of carriers, we must find $2pq$. Using the equations $p?2+2pq+q?2=1$ and $p+q=1$, determine the following: x Value of $q?2$:x Value of $q$:x Value of $p$:0× Carrier Frequency: 0 .