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(Solved): as indicated in Scheme 1, iodination of salicylamide may generate four regioisomers of the mono-iodi ...



as indicated in Scheme 1, iodination of salicylamide may generate four regioisomers of the mono-iodinated product. Even though a mixture of products is not ruled out, we have carefully optimized the reaction conditions to predominantly generate one of the indicated products. In the absence of melting points of authentic samples, which spectroscopic technique(s) will enable you to characterize the product and unambiguously identify the site of iodination of the aromatic ring?

Nal, \( \mathrm{NaOCl} \)
solvent = ethanol-water
2-hydroxybenzamide
mono-iodinated
(commonly known as
salicylamide
salicylam

Nal, \( \mathrm{NaOCl} \) solvent = ethanol-water 2-hydroxybenzamide mono-iodinated (commonly known as salicylamide salicylamide)


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