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(Solved): Although the predominant hemoglobin in newborns is HbF, adult hemoglobin (HbA) is typically expres ...



Although the predominant hemoglobin in newborns is \( \mathrm{HbF} \), adult hemoglobin \( (\mathrm{HbA}) \) is typically exp

Although the predominant hemoglobin in newborns is , adult hemoglobin is typically expressed as well. Mutant and wild-type variants can be distinguished through isoelectric focusing (IEF) electrophoresis. Shown below is an IEF gel of four samples from newborn patients of an extended family with a history of an E6V mutation in . Which newborn is most likely homozygous for this mutation? A. Patient B. Patient B (43\%) C. Patient C (27\%) D. Patient D (21\%)


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Mutation is a change in the DNA (
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