According to the synthesis of aspirin, o-hydroxybenzoic acid reacts first with acetyl chloride(nucleophilic acyl substitution), NOT pyridine(acid-base reaction). Explain the reason in detail.

Aspirin.

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According to the synthesis of aspirin, o-hydroxybenzoic acid reacts first with acetyl chloride(nucleophilic acyl substitution), NOT pyridine(acid-base reaction). Explain the reason in detail.

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Aspirin.

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