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(Solved): 6. You are studying a type of color blindness caused by a mutation in the OPN1LW gene located on th ...



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6. You are studying a type of color blindness caused by a mutation in the OPN1LW gene located on the X-chromosome (not in the pseudoautosomal region). An XX individual that is not color blind For this question, assume no variable penetrance or expressivity (e.g., caused by skewed Xinactivation). A. If the individual in generation I is homozygous wildtype, what does this suggest about the dominance relationship between the mutant and wildtype alleles of OPN1LW in this family? Explain. B. Still assume that the I-XX individual is homozygous wildtype. What is the probability that the offspring in generation III is red-green color blind if they are XY? Write out genotypes as part of your predictions/work. Use for the mutant allele ( is mutant, indicates it is on the chromosome) and for the wildtype allele. C. Why would it be very unexpected for the generation III child to be color blind if they are ? D. Brainstorm: Is there a possible way for the XX child in generation III to be color blind that does not involve variable penetrance or expressivity?


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