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(Solved): 6.) The figure below illustrates a hydropathy plot for an integral membrane protein. Above the Zero ...
6.) The figure below illustrates a hydropathy plot for an integral membrane protein. Above the Zero line are regions that are largely hydrophobic. What are the known secondary structural characteristics of the protein based upon this plot or what do you know about integral membrane proteins? Please draw a model for the protein in a membrane bilayer (or describe the protein) and illustrate the general (expected) location of the hydrophobic vs the hydrophilic residues.
Expert Answer
To understand the secondary structural characteristics of the protein based on the hydropathy plot, you would need to analyze the pattern of hydrophobic and hydrophilic regions. Hydrophobic regions are usually associated with transmembrane domains, where the protein spans across the lipid bilayer. Hydrophilic regions, on the other hand, are often found on the extracellular or cytoplasmic sides of the membrane.