(Solved): 6. (3 points total) Gunther's disease is a very rare genetic disorder that affect bone, muscle, tee ...

6. (3 points total) Gunther's disease is a very rare genetic disorder that affect bone, muscle, teeth and skin primarily. The gene implicated in this disorder is the uro-1 gene. Additionally, the disorder is caused by an autosomal recessive mutation in this gene that affects transcription. The incidence of this disorder in the population is roughly 1 affected individual in 1,000,000. Please answer the following questions and show your work to earn credit: a. (2 points) Please calculate the frequencies of the wild-type (p) and disease-causing allele (q) b. (1 point) Please calculate the frequency of obligate carriers in the population. 7. (2 points) Please show the formula that you would use when calculating heritability scores when doing twin studies. Please state how you would get an ${\mathrm{h}}^2$ of 1 , and what that score means.