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(Solved): 3. The most common way of determining a compound's lipid solubility is to measure the ratio of its ...




3. The most common way of determining a compounds lipid solubility is to measure the ratio of its solubility in an organic s
3. The most common way of determining a compound's lipid solubility is to measure the ratio of its solubility in an organic solvent (e.g. olive oil) to its solubility in water. This ratio is known as the compound's partition coefficient ( \( K \) ). The value of \( K \) for three anesthetic agents are: tetracaine, \( K=500 \); lidocaine, \( K=100 \); and procaine, \( K=5 \). To test the effectiveness of these three compounds in anesthetizing frog tadpoles, you add each agent separately to three beakers of water containing 100 swimming tadpoles to achieve the same final concentration and you count the number of tadpoles swimming at 1,5 , and \( 10 \mathrm{~min} \). You generate the Braph shown below. Which line represents which anesthetic and why do you conclude this? (3 pt)


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Partition coefficient describes a compound's lipid solubility that is how good a compound is to be soluble in a lipid substance. S
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