(Solved): 2. What are the monomers (one subunit) of a polypeptide called? - On the left half of the space bel ...

2. What are the monomers (one subunit) of a polypeptide called? - On the left half of the space below, draw a simple structure of a protein monomer with uncharged functional groups and $\mathrm{R}$ to denote the side chain. Circle and label the function groups and alpha carbon. - On the right half of the space, draw a similar structure with the two functional groups in their ionized (charged) forms. (At cellular pH both functional groups will be ionized. When we discuss whether this monomer is acidic/basic or polar/nonpolar then we are just referring to the variable side chains.) 3. After synthesis, a bond connects the two amino acids. Many subunits in a polymer make up the primary structure of a polypeptide. In the space below, draw a peptide dimer ( 2 amino acid connected by a bond, you can just use $R$ for side chain again). Label the two ends of the dimer with $\mathbf{N}$-terminus (to indicate amino group of the first amino acid) and $\mathbf{C}$-terminus (to indicate carboxyl group of the last amino acid). 4. The interactions on the backbone (not the side chains) contribute to the (circle one): primary/secondary/ tertiary/quaternary structure of the protein. On your drawing for \#3 indicated the partial charges on the atoms near the new covalent bond. For alpha-helix, these atoms of opposite partial charges that are four amino acids away are interacting to form bonds. 5. The interactions between side chains contribute to the primary/secondary/tertiary/quaternary (circle one or more) structure(s) of the protein. 6. What happens when you denature a protein with heat or $\mathrm{pH}$ changes? Which bonds are most likely broken?