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(Solved): 11. Synthesis: Propose a synthesis for each of the following starting with 2-bromobutane. a. 2- ...



11. Synthesis: Propose a synthesis for each of the following starting with 2-bromobutane.
a. 2-butene
b. 2-butyne
c. 2-butano

11. Synthesis: Propose a synthesis for each of the following starting with 2-bromobutane. a. 2-butene b. 2-butyne c. 2-butanol d. butane


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a.
2-butene from 2-bromobutane
When heated with strong bases, alkyl halides typically undergo a 1,2-elimination reactions to generate alkenes. Typical bases are NaOH or KOH 



Zaitsev's rule is an empirical rule used to predict the major products of elimination reactions. It states that in an elimination reaction the major product is the more stable alkene with the more highly substituted double bond.





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