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(Solved): 1. Transition, transversion, or NEITHER? Which type of mutation could result from (1) Deamination o ...
1. Transition, transversion, or NEITHER? Which type of mutation could result from (1) Deamination of bases? Which type of mutation could result from (2) UV damage? Defend your answer to both questions in a short paragraph describing what each type of damage does, and how it could lead to transition and/or transversion mutations OR NOT. You are free to supplement your answer with diagrams. 2. What are enzymes in common to BER, NER, and MMR? What processes are in common to each? 3. How many molecules of DNA does it take to make a visible band on a gel? It depends largely on the size of DNA (base pairs / molecular weight). So calculate how many molecules 500bp in length make up this band shown on the following gel. Assume that there are 100ng of DNA in that band. Think carefully about what information you need (you will need to remember some gen chem), show your calculation and then describe your approach in a short paragraph. Assume that there are equal amounts of each base present in the band (25%A, 25% T, 25%G,25% C).