1. The RNA-based COVID vaccines are composed of lipid nanoparticles which contain mRNA withina lipid-based cover (see Figure 1). Note two major functions for the lipid-based cover.2. The RNA to be delivered by the nanoparticle must be translated in the cytosol of the recipientcells in order to produce the SARS-CoV-2 spike protein (see top half of f solutionspile.com

Question

1. The RNA-based COVID vaccines are composed of lipid nanoparticles which contain mRNA within

a lipid-based cover (see Figure 1). Note two major functions for the lipid-based cover.

2. The RNA to be delivered by the nanoparticle must be translated in the cytosol of the recipient

cells in order to produce the SARS-CoV-2 spike protein (see top half of figure on page 191 of the

Nature article).

The line below is a generic representation of this RNA. Indicate on the RNA functional sequences

or components that would be expected to be found on this injected mature mRNA to ensure

that it would be effectively utilized to produce a viral spike protein in the cytosol of the recipient

cell. Below the drawing, indicate the function of each of the functional components that are

present in your mRNA.

5'---------------------------3'

3. Would it be helpful if the mRNA contained introns? Why or why not?

FIGURE 1 Cationic lipid, cholesterol, PEG nanoparticle + ORO + AAAAA + ???? ???? + + + 80-200 nm

Accepted Answer

Expert Answer to - 1. The RNA-based COVID vaccines are composed of lipid nanoparticles which contain mRNA withina lipid

Answer

Solution for - 1. The RNA-based COVID vaccines are composed of lipid nanoparticles which contain mRNA withina lipid

Answer

This an additional answer to - 1. The RNA-based COVID vaccines are composed of lipid nanoparticles which contain mRNA withina lipid

(Solved): 1. The RNA-based COVID vaccines are composed of lipid nanoparticles which contain mRNA withina lipid ...